One of the first steps in the tablet manufacturing process is the procurement of raw materials. This includes active pharmaceutical ingredients (APIs), excipients, and other materials needed to produce the tablets. The quality of these materials is crucial to the efficacy and safety of the final product. Once the raw materials are received, they undergo rigorous quality control checks to ensure they meet the required standards.
After the raw materials have been procured and tested, the next step in the tablet manufacturing process is granulation. Granulation is the process of forming granules from the powders, which helps to improve the flow properties and compressibility of the materials. There are different methods of granulation, including wet granulation, dry granulation, and direct compression. The choice of granulation method depends on the properties of the raw materials and the desired characteristics of the final tablet.
Flow Chart Of Tablet Manufacturing Process
Tablet Compression
Once the granules have been formed, they are ready for tablet compression. Tablet compression is the process of compressing the granules into tablets of the desired shape and size. This process is typically done using a tablet press machine, which applies pressure to the granules to form them into tablets. The tablets are then inspected for defects and imperfections before being packaged and distributed to the market.